
Patient-specific Microstructural and radIobiological model for persoNalised external beam radiatIONn therapy in localised tumourS
Our vision
Our vision is to drive a paradigm shift in radiotherapy planning and adaptation by developing a novel, patient-specific, and clinically compatible modeling framework. This framework will capture the microscopic characteristics of tumors and their interactions with radiation beams, paving the way for biologically targeted treatments and ultimately improving patient care.
The MINIONS project, funded by the European Union through an ERC Starting Grant (Chiara Paganelli, Principal Investigator), is carried out at the CartCasLab of the Politecnico di Milano.
Partners
The project involves a strategic collaboration with leading clinical partners in oncology and radiation oncology, enhancing its interdisciplinary nature and overall impact. This partnership brings together expertise from clinical research, data science, and technological innovation, ensuring that the developed models are tested, validated, and aligned with real-world clinical needs.
Our news
29/12/2025
PhD Opportunity at Politecnico di Milano in the Marie Skłodowska‑Curie RAPTORplus Project
The CartCasLab of Politecnico di Milano is offering a three-year PhD position within the prestigious Marie Skłodowska‑Curie RAPTORplus network, focusing on multi-scale modelling with quantitative MRI in particle therapy.
01/07/2025
June 27-28, 2025 – MINIONS Team at Adaptive PT Workshop
The MINIONS team joined the Online Adaptive PT Workshop in Pavia to present their initial project activities and discuss advances in adaptive particle therapy.
01/09/2024
MINIONS Project Kicks Off
The MINIONS project officially launched on September 1, 2024, to drive innovation in medical imaging and personalized radiotherapy.






